Article
Clinical Significance of C-MET Overexpression and Epidermal Growth Factor Receptor Mutation in Platinum-Based Adjuvant Chemotherapy Outcome in Surgically Resected Lung Adenocarcinoma.
Annals of surgical oncology - 1 Mar 2017
Kim In-Ho, Lee In Hee, Lee Ji Eun, Hong Sook Hee, Kim Tae-Jung, Lee Kyo-Young, Kim Young Kyoon, Kim Seung Joon, Sung Sook Whan, Park Jae Kil, Yoo Ie Ryung, Kim Yeon Sil, Kim Jung-Oh, Kang Jin Hyoung
Abstract excerpt
PURPOSE: We retrospectively assessed the role of C-MET expression and epidermal growth factor receptor (EGFR) mutation on survival following platinum-based adjuvant chemotherapy. The impact of C-MET on survival was also investigated in relation to EGFR mutation status. METHODS: We enrolled 311 patients with resected lung adenocarcinoma (high-risk stage 1B-3A), and performed immunohistochemistry (IHC) using C-MET-...
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