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Article

LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer.

Oncotarget - 13 Dec 2016

Henry Whitney S, Hendrickson David G, Beca Francisco, Glass Benjamin, Lindahl-Allen Marianne, He Lizhi, Ji Zhe, Struhl Kevin, Beck Andrew H, Rinn John L, Toker Alex

Abstract excerpt

Long non-coding RNAs (lncRNAs) have been implicated in normal cellular homeostasis as well as pathophysiological conditions, including cancer. Here we performed global gene expression profiling of mammary epithelial cells transformed by oncogenic v-Src, and identified a large subset of uncharacterized lncRNAs potentially involved in breast cancer development. Specifically, our analysis revealed a novel lncRNA,...

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Share to Class I Phosphatidylinositol 3-Kinases
Share to Mammary Glands, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MCF-7 Cells

Share to Neoplasm Invasiveness

Share to Oncogene Protein pp60(v-src)

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Share to STAT3 Transcription Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 27626181
DOI: 10.18632/oncotarget.11962
PMCID: PMC5347668

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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