Article
Phylogenetic analysis of Chikungunya virus in Colombia: Evidence of purifying selection in the E1 gene.
Biomedica : revista del Instituto Nacional de Salud - 23 Oct 2015
Laiton-Donato Katherine, Usme-Ciro José A, Rico Angélica, Pardo Lissethe, Martínez Camilo, Salas Daniela, Ardila Susanne, Páez Andrés
Abstract excerpt
INTRODUCTION: Chikungunya virus (CHIKV) is a single-stranded positive sense RNA virus that belongs to the Alphavirus genus of the family Togaviridae. Its genome is 11.8 kb in length, and three genotypes have been identified worldwide: Asian, East/Central/South African (ECSA) and West African. Chikungunya fever is an acute febrile disease transmitted by Aedes spp. that usually presents with polyarthralgia and...
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