Article
Elbasvir and grazoprevir for chronic hepatitis C genotypes 1 and 4.
Expert review of clinical pharmacology - 1 Nov 2016
El Kassas Mohamed, Elbaz Tamer, Abd El Latif Yasmeen, Esmat Gamal
Abstract excerpt
INTRODUCTION: During the last few years, treatment of hepatitis C virus (HCV) revolutionized with the appearance of direct antiviral agents especially for patients with HCV genotypes 1 and 4 infections. Elbasvir (NS5A inhibitor) and grazoprevir (NS3/4A protease inhibitor) are newly developed drugs that are presented in fixed dose combination tablets. Areas covered: This review covers the mechanism of action,...
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