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Article

Human vaginal fluid contains exosomes that have an inhibitory effect on an early step of the HIV-1 life cycle

17 Aug 2016

Abstract excerpt

OBJECTIVE: Vaginal transmission is crucial to the spread of HIV-1 around the world. It is not yet clear what type (s) of innate defenses against HIV-1 infection are present in the vagina. Here, we aimed to determine whether human vaginal fluid contains exosomes that may possess anti-HIV-1 activity. METHODS: The exosomal fraction was isolated from samples of vaginal fluids. The presence of exosomes was confirmed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27536982
DOI: 10.1097/qad.0000000000001236

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