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Article

Reduced expressions of connexin 43 and VEGF in the first-trimester tissues from women with recurrent pregnancy loss

17 Aug 2016

Abstract excerpt

BACKGROUND: Approximately 45-50 % of the recurrent pregnancy loss (RPL) remain(s) unexplained that challenges its clinical management. Formation and development of placenta as well as angiogenesis are critical for successful pregnancy. Vascular endothelial growth factor (VEGF) and connexin 43 (Cx43) play important roles in angiogenesis and placenta development and aberration of these have been linked to RPL. We...

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PMID: 27535546
DOI: 10.1186/s12958-016-0179-4

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