Article
Genome-Wide Association Studies with a Genomic Relationship Matrix: A Case Study with Wheat and Arabidopsis.
G3 (Bethesda, Md.) - 13 Oct 2016
Gianola Daniel, Fariello Maria I, Naya Hugo, Schön Chris-Carolin
Abstract excerpt
Standard genome-wide association studies (GWAS) scan for relationships between each of p molecular markers and a continuously distributed target trait. Typically, a marker-based matrix of genomic similarities among individuals ( G: ) is constructed, to account more properly for the covariance structure in the linear regression model used. We show that the generalized least-squares estimator of the regression of...
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