Article
Pairwise Kinship Analysis by the Index of Chromosome Sharing Using High-Density Single Nucleotide Polymorphisms.
PloS one - 1 Jan 2016
Morimoto Chie, Manabe Sho, Kawaguchi Takahisa, Kawai Chihiro, Fujimoto Shuntaro, Hamano Yuya, Yamada Ryo, Matsuda Fumihiko, Tamaki Keiji
Abstract excerpt
We developed a new approach for pairwise kinship analysis in forensic genetics based on chromosomal sharing between two individuals. Here, we defined "index of chromosome sharing" (ICS) calculated using 174,254 single nucleotide polymorphism (SNP) loci typed by SNP microarray and genetic length of the shared segments from the genotypes of two individuals. To investigate the expected ICS distributions from first-...
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