Article
Construction and characterization of a full-length cDNA infectious clone of emerging porcine Senecavirus A.
Virology - 1 Oct 2016
Chen Zhenhai, Yuan Fangfeng, Li Yanhua, Shang Pengcheng, Schroeder Robin, Lechtenberg Kelly, Henningson Jamie, Hause Benjamin, Bai Jianfa, Rowland Raymond R R, Clavijo Alfonso, Fang Ying
Abstract excerpt
A full-length cDNA infectious clone, pKS15-01-Clone, was constructed from an emerging Senecavirus A (SVA; strain KS15-01). To explore the potential use as a viral backbone for expressing marker genes, the enhanced green fluorescent protein (EGFP)-tagged reporter virus (vKS15-01-EGFP) was generated using reverse genetics. Compared to the parental virus, the pKS15-01-Clone derived virus (vKS15-01-Clone) replicated...
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