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Article

Caging and Uncaging Genetics.

PLoS biology - 1 Jul 2016

Little Tom J, Colegrave Nick

Abstract excerpt

It is important for biology to understand if observations made in highly reductionist laboratory settings generalise to harsh and noisy natural environments in which genetic variation is sorted to produce adaptation. But what do we learn by studying, in the laboratory, a genetically diverse population that mirrors the wild? What is the best design for studying genetic variation? When should we consider it at all?...

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Identifiers

PMID: 27458971
DOI: 10.1371/journal.pbio.1002525
PMCID: PMC4961361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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