Article
[Association of NLRP3 gene single nucleotide polymorphisms with metabolic syndrome].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Aug 2016
Zhang Li, Zhang Dongmei, Zheng Yingying, Hu Zhengmao, Zeng Yi, Yue Fangzhi
Abstract excerpt
OBJECTIVE: To assess the association of single nucleotide polymorphisms (SNPs) of NLRP3 gene with metabolic syndrome (MetS). METHODS: A total of 885 subjects including 410 MetS patients and 475 healthy controls were recruited. MetS was defined based on the National Cholesterol Education Program in Adult Treatment Panel III criteria. Two common SNPs of the NLRP3 gene, rs10754558 and rs4612666, were detected using...
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