Article
Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population.
Scientific reports - 13 Jul 2016
Lee I Russel, Molton James S, Wyres Kelly L, Gorrie Claire, Wong Jocelyn, Hoh Chu Han, Teo Jeanette, Kalimuddin Shirin, Lye David C, Archuleta Sophia, Holt Kathryn E, Gan Yunn-Hwen
Abstract excerpt
Hypervirulent Klebsiella pneumoniae is an emerging cause of community-acquired pyogenic liver abscess. First described in Asia, it is now increasingly recognized in Western countries, commonly afflicting those with Asian descent. This raises the question of genetic predisposition versus geospecific strain acquisition. We leveraged on the Antibiotics for Klebsiella Liver Abscess Syndrome Study (A-KLASS) clinical...
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