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Article

Infectivity of Immature Neurons to Zika Virus: A Link to Congenital Zika Syndrome

24 Jun 2016

Abstract excerpt

BACKGROUND: Epidemiological data strongly suggest that microcephaly cases in Brazil are associated with the ongoing epidemic of Zika virus (ZIKV). In order to further solidify the possible link, we investigated the infectivity of ZIKV using various neuroblastoma (NB) cell lines. METHODS: Six undifferentiated, two terminally differentiated and two retinoic acid (RA) -induced, partially differentiated cell lines...

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PMID: 27364784
DOI: 10.1016/j.ebiom.2016.06.026

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