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Circulating miRNAs are generic and versatile therapeutic monitoring biomarkers in muscular dystrophies

21 Jun 2016

Abstract excerpt

The development of medical approaches requires preclinical and clinical trials for assessment of therapeutic efficacy. Such evaluation entails the use of biomarkers, which provide information on the response to the therapeutic intervention. One newly-proposed class of biomarkers is the microRNA (miRNA) molecules. In muscular dystrophies (MD), the dysregulation of miRNAs was initially observed in muscle biopsy and...

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PMID: 27323895
DOI: 10.1038/srep28097

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