Article
Mutations in the N-terminal kinase-like domain of the repressor of photomorphogenesis SPA1 severely impair SPA1 function but not light responsiveness in Arabidopsis.
The Plant journal : for cell and molecular biology - 1 Oct 2016
Holtkotte Xu, Dieterle Stefan, Kokkelink Leonie, Artz Oliver, Leson Lisa, Fittinghoff Kirsten, Hayama Ryosuke, Ahmad Margaret, Hoecker Ute
Abstract excerpt
The COP1/SPA complex is an E3 ubiquitin ligase that acts as a key repressor of photomorphogenesis in dark-grown plants. While both COP1 and the four SPA proteins contain coiled-coil and WD-repeat domains, SPA proteins differ from COP1 in carrying an N-terminal kinase-like domain that is not present in COP1. Here, we have analyzed the effects of deletions and missense mutations in the N-terminus of SPA1 when...
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