Article
Sequencing of 16S rRNA reveals a distinct salivary microbiome signature in Behçet's disease.
Clinical immunology (Orlando, Fla.) - 1 Aug 2016
Coit Patrick, Mumcu Gonca, Ture-Ozdemir Filiz, Unal Ali Ugur, Alpar Ugur, Bostanci Nagihan, Ergun Tulin, Direskeneli Haner, Sawalha Amr H
Abstract excerpt
Behçet's disease (BD) is characterized by recurrent oro-genital ulcers, mucocutaneous lesions, and serious organ involvement. We investigated the salivary microbiome in BD using high-throughput sequencing of the 16S rRNA V4 region. Stimulated saliva samples were collected from 31 BD patients and 15 healthy controls, and in 9 BD patients, a second saliva sample was collected following dental and periodontal...
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