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A comprehensive comparison between pediatric and adult patients with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenopathy (PFAPA) syndrome.

Clinical rheumatology - 1 Feb 2017

Rigante Donato, Vitale Antonio, Natale Marco Francesco, Lopalco Giuseppe, Andreozzi Laura, Frediani Bruno, D'Errico Francesca, Iannone Florenzo, Cantarini Luca

Abstract excerpt

Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenopathy (PFAPA) syndrome is a mysterious disorder characterized by periodically recurrent fevers, oropharyngeal inflammation, and adenitis, which mainly affects children, though in very recent times, it has been also recognized in adulthood. We enrolled 115 unrelated pediatric and adult patients with history of periodic fevers who fulfilled the...

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PMID: 27251674
DOI: 10.1007/s10067-016-3317-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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