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Article

How Far Do We Go With Genetic Evaluation? Gene, Panel, and Tumor Testing.

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting - 1 Jan 2016

Lynce Filipa, Isaacs Claudine

Abstract excerpt

The traditional model by which an individual was identified as harboring a hereditary susceptibility to cancer was to test for a mutation in a single gene or a finite number of genes associated with a particular syndrome (e.g., BRCA1 and BRCA2 for hereditary breast and ovarian cancer or mismatch repair genes for Lynch syndrome). The decision regarding which gene or genes to test for was based on a review of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27249773
DOI: 10.1200/EDBK_160391
PMCID: PMC6054472

Genes

BRCA1
BRCA2

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