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Article

Efficacy of daclatasvir/asunaprevir according to resistance-associated variants in chronic hepatitis C with genotype 1.

Journal of gastroenterology - 1 Jan 2017

Iio Etsuko, Shimada Noritomo, Abe Hiroshi, Atsukawa Masanori, Yoshizawa Kai, Takaguchi Koichi, Eguchi Yuichiro, Nomura Hideyuki, Kuramitsu Tomoyuki, Kang Jong-Hon, Matsui Takeshi, Hirashima Noboru, Tsubota Akihito, Kusakabe Atsunori, Hasegawa Izumi, Miyaki Tomokatsu, Shinkai Noboru, Fujiwara Kei, Nojiri Shunsuke, Tanaka Yasuhito

Abstract excerpt

BACKGROUND: The present study explored the treatment outcome of daclatasvir (DCV) and asunaprevir (ASV) therapy combining oral direct-acting antiviral agents (DAAs) for chronic hepatitis C (HCV) including liver cirrhosis according to resistance-associated variants (RAVs) in NS3/NS5A region. METHODS: Overall, 641 patients enrolled in Japan with HCV-1b received DCV and ASV for 24 weeks. Baseline drug-resistant...

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Identifiers

PMID: 27236547
DOI: 10.1007/s00535-016-1225-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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