Article
Lysosomal Acid Lipase Activity Is Reduced Both in Cryptogenic Cirrhosis and in Cirrhosis of Known Etiology.
PloS one - 1 Jan 2016
Vespasiani-Gentilucci Umberto, Gallo Paolo, Piemonte Fiorella, Riva Elisabetta, Porcari Aldostefano, Vorini Ferruccio, Tozzi Giulia, Piccioni Livia, Galati Giovanni, De Vincentis Antonio, Carotti Simone, Morini Sergio, D'Amico Jessica, Angeletti Silvia, Pedone Claudio, Picardi Antonio
Abstract excerpt
CONCLUSION: Liver cirrhosis is characterized by a severe acquired reduction of LAL-activity, the precise causes and consequences of which need to be further addressed. DBS-determined lysosomal enzyme activities seem to be affected by white blood cell and platelet counts, and the specificity of these tests can be reduced when applied to determined populations, such as cirrhotics.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.