Article
Distinguishing the genotype 1 genes and proteins of human Wa-like rotaviruses vs. porcine rotaviruses.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2016
Silva Fernanda D F, Gregori F, McDonald Sarah M
Abstract excerpt
Group A rotaviruses (RVAs) are 11-segmented, double-stranded RNA viruses and important causes of gastroenteritis in the young of many animal species. Previous studies have suggested that human Wa-like RVAs share a close evolutionary relationship with porcine RVAs. Specifically, the VP1-VP3 and NSP2-5/6 genes of these viruses are usually classified as genotype 1 with >81% nucleotide sequence identity. Yet, it...
Topics
- Animals
- Computational Biology
- Evolution, Molecular
- Genotype
- Humans
- Phylogeny
- Rotavirus
- Sequence Analysis, RNA
- Swine
- Viral Proteins
