Article
Pretreatment gut microbiome predicts chemotherapy-related bloodstream infection.
Genome medicine - 28 Apr 2016
Montassier Emmanuel, Al-Ghalith Gabriel A, Ward Tonya, Corvec Stephane, Gastinne Thomas, Potel Gilles, Moreau Phillipe, de la Cochetiere Marie France, Batard Eric, Knights Dan
Abstract excerpt
BACKGROUND: Bacteremia, or bloodstream infection (BSI), is a leading cause of death among patients with certain types of cancer. A previous study reported that intestinal domination, defined as occupation of at least 30 % of the microbiota by a single bacterial taxon, is associated with BSI in patients undergoing allo-HSCT. However, the impact of the intestinal microbiome before treatment initiation on the risk...
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