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Article

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy: report of three cases from Iran.

Journal of pediatric endocrinology & metabolism : JPEM - 1 Aug 2016

Seifi-Alan Mahnaz, Shamsi Roshanak, Setoodeh Aria, Sayarifard Fatemeh, Aghasi Parisa, Kompani Farzad, Ghafouri-Fard Soudeh, Abbasi Farzaneh

Abstract excerpt

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), also named as autoimmune polyglandular syndrome (APS) type 1, is a rare autosomal recessive disorder caused by mutations in autoimmune regulator (AIRE) gene. It is distinguished by an immune-mediated damage of endocrine tissues, chronic candidiasis, and ectodermal disorder. APECED has been shown to be frequent in some populations including...

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Identifiers

PMID: 27105486
DOI: 10.1515/jpem-2016-0017

Genes

AIRE

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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