Article
Phenotypic and molecular characterization of resistance to macrolides, lincosamides and type B streptogramin of clinical isolates of Staphylococcus spp. of a university hospital in Recife, Pernambuco, Brazil.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000
Pereira Jussyêgles Niedja da Paz, Rabelo Marcelle Aquino, Lima Jailton Lobo da Costa, Neto Armando Monteiro Bezerra, Lopes Ana Catarina de Souza, Maciel Maria Amélia Vieira
Abstract excerpt
INTRODUCTION: There is a mechanism of macrolide resistance in Staphylococcus spp. which also affects the lincosamides and type B streptogramins characterizing the so-called MLSB resistance, whose expression can be constitutive (cMLSB) or inducible (iMLSB) and is encoded mainly by ermA and ermC genes. The cMLSB resistance is easily detected by susceptibility testing used in the laboratory routine, but iMLSB...
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