Article
Clinical and genetic features of lung squamous cell cancer in never-smokers.
Oncotarget - 14 Jun 2016
Huang Yangle, Wang Rui, Pan Yunjian, Zhang Yang, Li Hang, Cheng Chao, Zheng Difan, Zheng Shanbo, Li Yuan, Shen Xuxia, Hu Haichuan, Cai Deng, Wang Shengfei, Zhang Yawei, Xiang Jiaqing, Sun Yihua, Zhang Jie, Chen Haiquan
Abstract excerpt
To evaluate the importance of specific driver mutations to the development and outcome of lung squamous cell cancer (SQCC) in never-smokers, we assessed the clinicopathological characteristics and outcomes of 597 patients who underwent complete resection of SQCCs. In total, 88 (14.7%) never-smokers and 509 (85.3%) ever-smokers were compared. The never-smokers included more females (42.05% vs. 1.57%, P < 0.001)...
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