Article
Dose-dependent cannabis use, depressive symptoms, and FAAH genotype predict sleep quality in emerging adults: a pilot study.
The American journal of drug and alcohol abuse - 1 Jul 2016
Maple Kristin E, McDaniel Kymberly A, Shollenbarger Skyler G, Lisdahl Krista M
Abstract excerpt
BACKGROUND: Cannabis has been shown to affect sleep in humans. Findings from animal studies indicate that higher endocannabinoid levels promote sleep, suggesting that chronic use of cannabis, which downregulates endocannabinoid activity, may disrupt sleep. OBJECTIVES: This study sought to determine if past-year cannabis use and genes that regulate endocannabinoid signaling, FAAH rs324420 and CNR1 rs2180619,...
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