Article
Glypican-4 gene polymorphism (rs1048369) and susceptibility to Epstein-Barr virus-associated and -negative gastric carcinoma.
Virus research - 15 Jul 2016
Zhao Danrui, Liu Shuzhen, Sun Lingling, Zhao Zhenzhen, Liu Song, Kuang Xiaojing, Shu Jun, Luo Bing
Abstract excerpt
BACKGROUND/AIMS: Gastric cancer (GC) is one of the most common malignant tumors in China and single nucleotide polymorphisms (SNPs) have been found to be highly related to GC carcinogenesis. Glypican-4 (GPC4), a member of the heparan sulphate proteoglycan family, plays an important role in the regulation of cell growth and differentiation. However, little is known about polymorphisms of GPC4 gene and their...
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