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Article

MicroRNA Profiling in Aqueous Humor of Individual Human Eyes by Next-Generation Sequencing

11 Apr 2016

Abstract excerpt

PURPOSE: Extracellular microRNAs (miRNAs) in aqueous humor were suggested to have a role in transcellular signaling and may serve as disease biomarkers. The authors adopted next-generation sequencing (NGS) techniques to further characterize the miRNA profile in single samples of 60 to 80 μL human aqueous humor. METHODS: Samples were obtained at the outset of cataract surgery in nine independent, otherwise healthy...

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PMID: 27064390
DOI: 10.1167/iovs.15-17828

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