Article
Transcription Profile in Sporadic Multiple Symmetric Lipomatosis Reveals Differential Expression at the Level of Adipose Tissue-Derived Stem Cells.
Plastic and reconstructive surgery - 1 Apr 2016
Prantl Lukas, Schreml Julia, Gehmert Sebastian, Klein Silvan, Bai Xiaowen, Zeitler Katharina, Schreml Stephan, Alt Eckhard, Gehmert Sanga, Felthaus Oliver
Abstract excerpt
BACKGROUND: The cause of the rare fat distribution disorder multiple symmetric lipomatosis is unknown. Independent reports suggest a higher proliferative activity, hormone resistance, and involvement of mitochondrial function in the disease. METHODS: The authors performed morphologic comparison of affected and unaffected tissues in five unrelated patients and generated adipose-derived stem cell cultures from the...
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