Article
Efficacy of Direct-Acting Antiviral Combination for Patients With Hepatitis C Virus Genotype 1 Infection and Severe Renal Impairment or End-Stage Renal Disease.
Gastroenterology - 1 Jun 2016
Pockros Paul J, Reddy K Rajender, Mantry Parvez S, Cohen Eric, Bennett Michael, Sulkowski Mark S, Bernstein David E, Cohen Daniel E, Shulman Nancy S, Wang Deli, Khatri Amit, Abunimeh Manal, Podsadecki Thomas, Lawitz Eric
Abstract excerpt
BACKGROUND & AIMS: Although hepatitis C virus (HCV) infection is common in patients with end-stage renal disease, highly efficacious, well-tolerated, direct-acting antiviral regimens have not been extensively studied in this population. We investigated the safety and efficacy of ombitasvir co-formulated with paritaprevir and ritonavir, administered with dasabuvir (with or without ribavirin) in a prospective study...
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