Laboratory parameters provided by Advia 2120 analyser identify structural haemoglobinopathy carriers and discriminate between Hb S trait and Hb C trait.

doi:10.1136/jclinpath-2015-203556

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Article

Laboratory parameters provided by Advia 2120 analyser identify structural haemoglobinopathy carriers and discriminate between Hb S trait and Hb C trait.

Journal of clinical pathology - 1 Oct 2016

Velasco-Rodríguez Diego, Alonso-Domínguez Juan-Manuel, González-Fernández Fernando-Ataúlfo, Muriel Alfonso, Abalo Lorena, Sopeña María, Villarrubia Jesús, Ropero Paloma, Plaza María Paz, Tenorio María, Jiménez-Martín Ana, Moreno Gemma, Martínez-Nieto Jorge, de la Fuente-Gonzalo Félix, Fernández-Escribano Marina, López-Jiménez Francisco Javier, Cava Fernando

Abstract excerpt

BACKGROUND: Haemoglobinopathies have spread owing to human migration, and the number of people needing diagnosis and management of these conditions is increasing. Clinicians need to accurately identify carriers and provide adequate genetic counselling in order to prevent the occurrence of homozygous or compound heterozygous offspring. OBJECTIVES: To identify red blood cell (RBC) laboratory parameters that...

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PMID: 26915371
DOI: 10.1136/jclinpath-2015-203556

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