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Article

Emergence of nontoxic mutants as revealed by single filament analysis in bloom-forming cyanobacteria of the genus Planktothrix.

BMC microbiology - 25 Feb 2016

Chen Qin, Christiansen Guntram, Deng Li, Kurmayer Rainer

Abstract excerpt

BACKGROUND: Bloom-forming cyanobacteria cause toxic algae outbreaks in lakes and reservoirs. We aimed to explore and quantify mutation events occurring within the large mcy gene cluster (55 kbp) encoding microcystin (MC) biosynthesis that inactivate MC net production. For this purpose we developed a workflow to detect mutations in situ occurring anywhere within the large mcy gene cluster as amplified from one...

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PMID: 26911978
DOI: 10.1186/s12866-016-0639-1
PMCID: PMC4766695

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