Article
Association of angiotensin-converting enzyme gene polymorphisms with Crohn's disease in a Chinese Han population.
International journal of clinical and experimental pathology - 1 Jan 2015
Zhou Jie, Zheng Sichang, Wang Zhengting, Fan Rong, Yuan Jielu, Zhong Jie
Abstract excerpt
OBJECTIVE: To investigate whether Angiotensin-converting enzyme (ACE) gene polymorphisms alter the susceptibility of a Chinese Han population to Crohn's disease (CD). METHODS: Blood samples were collected from patients with CD and from healthy control subjects for analyzing SNP rs4291 (promoter, A262T), SNP rs4343 (exon 16, A11860G), and rs4646994 (intron 16, Alu insertion/deletion). Allele and genotype...
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