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Chromosomal copy number analysis on chorionic villus samples from early spontaneous miscarriages by high throughput genetic technology

26 Jan 2016

Abstract excerpt

BACKGROUND: About 10 -15 % of all clinically recognized pregnancies result in spontaneous miscarriages, and chromosomal abnormalities are the most common reason. The conventional karyotyping on chorionic villus samples (CVSs) is limited by cell culture and its resolution. This study aimed at evaluating the efficiency of the application of high throughput genetic technology, including array comparative genomic...

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Share to Genetic Syndromes and Imprinting
Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics

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PMID: 26819630
DOI: 10.1186/s13039-015-0210-z

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