Article
Prevalence of Monogenic Causes in Pediatric Patients with Nephrolithiasis or Nephrocalcinosis.
Clinical journal of the American Society of Nephrology : CJASN - 7 Apr 2016
Braun Daniela Anne, Lawson Jennifer Ashley, Gee Heon Yung, Halbritter Jan, Shril Shirlee, Tan Weizhen, Stein Deborah, Wassner Ari J, Ferguson Michael A, Gucev Zoran, Fisher Brittany, Spaneas Leslie, Varner Jennifer, Sayer John A, Milosevic Danko, Baum Michelle, Tasic Velibor, Hildebrandt Friedhelm
Abstract excerpt
BACKGROUND AND OBJECTIVES: Nephrolithiasis is a prevalent condition that affects 10%-15% of adults in their lifetime. It is associated with high morbidity due to colicky pain, the necessity for surgical intervention, and sometimes progression to CKD. In recent years, multiple monogenic causes of nephrolithiasis and nephrocalcinosis have been identified. However, the prevalence of each monogenic gene in a...
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