Article
First insight into the genetic population structure of Mycobacterium tuberculosis isolated from pulmonary tuberculosis patients in Egypt.
Tuberculosis (Edinburgh, Scotland) - 1 Jan 2016
Diab Hassan Mahmoud, Nakajima Chie, Kotb Saber A, Mokhtar Alaa, Khder Nagwa F M, Abdelaal Ahmed S A, Hegazy Azza, Poudel Ajay, Shah Yogendra, Suzuki Yasuhiko
Abstract excerpt
The present study aimed to assess the population structure of Mycobacterium tuberculosis (MTB) isolates from Egypt. A total of 230 MTB isolates were analysed using spoligotyping, large sequence polymorphism (LSPs), mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) typing and multi-locus sequence typing (MLST). The majority of isolates (93.0%) belonged to lineage 4, including...
Topics
- Bacteriological Techniques
- DNA, Bacterial
- Egypt
- Evolution, Molecular
- Genotype
- Humans
- Interspersed Repetitive Sequences
- Minisatellite Repeats
- Molecular Epidemiology
- Mycobacterium tuberculosis
