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Article

microRNA-23a inhibits osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting LRP5.

The international journal of biochemistry & cell biology - 1 Mar 2016

Li Tao, Li Hongling, Wang Yingzhen, Li Tangping, Fan Junfen, Xiao Ke, Zhao Robert Chunhua, Weng Xisheng

Abstract excerpt

Emerging evidence indicates that microRNAs (miRNA, or miR) play vital roles in regulating osteogenic differentiation of bone marrow-derived mesenchymal stem cells (BMSCs). Elucidation of the molecular mechanisms that govern BMSCs osteogenic differentiation is of paramount importance for improving the treatment of bone-related diseases. In our current study, we investigated the role of miR-23a in BMSCs...

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Source

Identifiers

PMID: 26774446
DOI: 10.1016/j.biocel.2016.01.004

Genes

LRP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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