Article
Postibrutinib outcomes in patients with mantle cell lymphoma.
Blood - 24 Mar 2016
Martin Peter, Maddocks Kami, Leonard John P, Ruan Jia, Goy Andre, Wagner-Johnston Nina, Rule Simon, Advani Ranjana, Iberri David, Phillips Tycel, Spurgeon Stephen, Kozin Eliana, Noto Katherine, Chen Zhengming, Jurczak Wojciech, Auer Rebecca, Chmielowska Ewa, Stilgenbauer Stephan, Bloehdorn Johannes, Portell Craig, Williams Michael E, Dreyling Martin, Barr Paul M, Chen-Kiang Selina, DiLiberto Maurizio, Furman Richard R, Blum Kristie A
Abstract excerpt
Despite unprecedented clinical activity in mantle cell lymphoma (MCL), primary and acquired resistance to ibrutinib is common. The outcomes and ideal management of patients who experience ibrutinib failure are unclear. We performed a retrospective cohort study of all patients with MCL who experienced disease progression while receiving ibrutinib across 15 international sites. Medical records were evaluated for...
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