Article
Ultra-deep sequencing of VHSV isolates contributes to understanding the role of viral quasispecies.
Veterinary research - 8 Jan 2016
Schönherz Anna A, Lorenzen Niels, Guldbrandtsen Bernt, Buitenhuis Bart, Einer-Jensen Katja
Abstract excerpt
The high mutation rate of RNA viruses enables the generation of a genetically diverse viral population, termed a quasispecies, within a single infected host. This high in-host genetic diversity enables an RNA virus to adapt to a diverse array of selective pressures such as host immune response and switching between host species. The negative-sense, single-stranded RNA virus, viral haemorrhagic septicaemia virus...
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