Article
Structural Evolution of the Emerging 2014-2015 GII.17 Noroviruses.
Journal of virology - 23 Dec 2015
Singh Bishal Kumar, Koromyslova Anna, Hefele Lisa, Gürth Clara, Hansman Grant S
Abstract excerpt
Recent reports suggest that human genogroup II genotype 17 (GII.17) noroviruses are increasing in prevalence. We analyzed the evolutionary changes of three GII.17 capsid protruding (P) domains. We found that the GII.17 P domains had little cross-reactivity with antisera raised against the dominant GII.4 strains. X-ray structural analysis of GII.17 P domains from 2002 to 2014 and 2015 suggested that...
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