Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microbial, host and xenobiotic diversity in the cystic fibrosis sputum metabolome

1 Dec 2015

Abstract excerpt

Cystic fibrosis (CF) lungs are filled with thick mucus that obstructs airways and facilitates chronic infections. Pseudomonas aeruginosa is a significant pathogen of this disease that produces a variety of toxic small molecules. We used molecular networking-based metabolomics to investigate the chemistry of CF sputa and assess how the microbial molecules detected reflect the microbiome and clinical culture...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial biofilms and quorum sensing
Share to Cystic Fibrosis Research Advances
Share to Gut microbiota and health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26623545
DOI: 10.1038/ismej.2015.207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microbial, host and xenobiotic diversity in the cystic fibrosis sputum metabolomePMID 26623545Read ↗

Differential Metabolite Production Underlies Disruption of the Cystic Fibrosis Airway Microbiota by PathogensSemantic proximity Read ↗

Microbiota and Metabolite Profiling Reveal Specific Alterations in Bacterial Community Structure and Environment in the Cystic Fibrosis Airway during ExacerbationSemantic proximity Read ↗

Untargeted Metabolomics Reveals Species-Specific Metabolite Production and Shared Nutrient Consumption by Pseudomonas aeruginosa and Staphylococcus aureusSemantic proximity Read ↗

The Molecular and Microbial Microenvironments in Chronically Diseased LungsSemantic proximity Read ↗

Fermentation products in the cystic fibrosis airways induce aggregation and dormancy-associated expression profiles in a CF clinical isolate of Pseudomonas aeruginosaSemantic proximity Read ↗

Molecular and Microbial Microenvironments in Chronically Diseased Lungs Associated with Cystic FibrosisSemantic proximity Read ↗

Metabolomic Profiling of Burkholderia Cenocepacia in Synthetic Cystic Fibrosis Sputum Media Reveals Nutrient Environment-Specific Production of Virulence FactorsSemantic proximity Read ↗

High-Resolution Longitudinal Dynamics of the Cystic Fibrosis Sputum Microbiome and Metabolome through Antibiotic TherapySemantic proximity Read ↗

Metabolomic profiling of Burkholderia cenocepacia in synthetic cystic fibrosis sputum medium reveals nutrient environment-specific production of virulence factorsSemantic proximity Read ↗

Microbiome in cystic fibrosis: Shaping polymicrobial interactions for advances in antibiotic therapySemantic proximity Read ↗

Metabolism and Pathogenicity ofPseudomonas aeruginosaInfections in the Lungs of Individuals with Cystic FibrosisSemantic proximity Read ↗

Metabolic Modeling of Cystic Fibrosis Airway Communities Predicts Mechanisms of Pathogen DominanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.