Article
Determination of Heavy Metal Concentrations in Normal and Pathological Human Endometrial Biopsies and In Vitro Regulation of Gene Expression by Metals in the Ishikawa and Hec-1b Endometrial Cell Line.
PloS one - 1 Jan 2015
Guyot Erwan, Solovyova Yevgeniya, Tomkiewicz Céline, Leblanc Alix, Pierre Stéphane, El Balkhi Souleiman, Le Frère-Belda Marie-Aude, Lecuru Fabrice, Poupon Joël, Barouki Robert, Aggerbeck Martine, Coumoul Xavier
Abstract excerpt
It is well known that several metals, such as lead, mercury, cadmium, and vanadium, can mimic the effects of estrogens (metallo-estrogens). Nevertheless, there are only a few studies that have assessed the effects of toxic metals on the female genital tract and, in particular, endometrial tissue. In this context, we measured the concentrations of several trace elements in human endometrial tissue samples from...
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