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Article

Attachment style and oxytocin receptor gene variation interact in influencing social anxiety.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Jan 2016

Notzon S, Domschke K, Holitschke K, Ziegler C, Arolt V, Pauli P, Reif A, Deckert J, Zwanzger P

Abstract excerpt

OBJECTIVES: Social anxiety has been suggested to be promoted by an insecure attachment style. Oxytocin is discussed as a mediator of trust and social bonding as well as a modulator of social anxiety. Applying a gene-environment (G × E) interaction approach, in the present pilot study the main and interactive effects of attachment styles and oxytocin receptor (OXTR) gene variation were probed in a combined risk...

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Source

Identifiers

PMID: 26488131
DOI: 10.3109/15622975.2015.1091502

Genes

OXTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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