Article
From rare to common and back again: 60years of lysosomal dysfunction.
Molecular genetics and metabolism - 1 Feb 2016
Coutinho Maria Francisca, Alves Sandra
Abstract excerpt
Sixty years after its discovery, the lysosome is no longer considered as cell's waste bin but as an organelle playing a central role in cell metabolism. Besides its well known association with lysosomal storage disorders (mostly rare and life-threatening diseases), recent data have shown that the lysosome is also a player in some of the most common conditions of our time; and, perhaps even most important, it is...
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