Article
Genetics of essential tremor.
Parkinsonism & related disorders - 1 Jan 2016
Tio Murni, Tan Eng-King
Abstract excerpt
Essential tremor is one of the most common adult-onset movement disorders. While it is recognized that genes play a major role in ET with ≥50% of the affected individuals having a positive family history, identifying underlying genes in both monogenic and complex forms of ET has been a challenging task. Recent discoveries linking LINGO1, FUS and TENM4 to essential tremor have been met with cautious optimism since...
Topics
- Animals
- Essential Tremor
- Genetic Predisposition to Disease
- Humans
- Membrane Proteins
- Nerve Tissue Proteins
- RNA-Binding Protein FUS
