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Article

Bevacizumab plus XELOX as first-line treatment of metastatic colorectal cancer: The OBELIX study.

World journal of gastroenterology - 21 Jun 2015

Antonuzzo Lorenzo, Giommoni Elisa, Pastorelli Davide, Latiano Tiziana, Pavese Ida, Azzarello Domenico, Aieta Michele, Pastina Ilaria, Di Fabio Francesca, Bertolini Alessandro, Corsi Domenico Cristiano, Mogavero Selene, Angelini Valentina, Pazzagli Mario, Di Costanzo Francesco

Abstract excerpt

AIM: To confirm the efficacy and safety of bevacizumab/XELOX combination for the treatment of locally advanced or metastatic colorectal cancer (CRC) in Italy. METHODS: This multicentric, prospective, open-label study included patients with CRC previously untreated with chemotherapy. Patients were administered bevacizumab in combination with XELOX. The primary efficacy end-point was progression-free survival...

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Identifiers

PMID: 26109816
DOI: 10.3748/wjg.v21.i23.7281
PMCID: PMC4476891

Genes

BRAF
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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