Article
The C4280A (rs5705) gene polymorphism of the renin (REN) gene is associated with risk of developing coronary artery disease, but not with restenosis after coronary stenting.
Experimental and molecular pathology - 1 Aug 2015
Fragoso Jose Manuel, Alvarez-León Edith, Delgadillo-Rodríguez Hilda, Arellano-González Marva, López-Pacheco Filogonio Caín, Cruz-Robles David, Peña-Duque Marco Antonio, Pérez-Méndez Oscar, Martínez-Ríos Marco Antonio, Vargas-Alarcón Gilberto
Abstract excerpt
The aim of the present study was to evaluate the role of AGT and REN gene polymorphisms as susceptibility markers for coronary artery disease (CAD) and/or restenosis after coronary stent placement in a group of Mexican patients. Five polymorphisms of the AGT (rs699, rs4762, rs5051, rs5049, rs5046) and two of the REN (, ) genes were analyzed by 5' exonuclease TaqMan genotyping assays in 240 patients...