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Article

[New targets and new drugs in thoracic oncology].

Revue des maladies respiratoires - 1 Oct 2015

Rouviere D, Bousquet E, Pons E, Milia J-D, Guibert N, Mazieres J

Abstract excerpt

A number of mechanisms that drive oncogenesis have been deciphered over the last 20 years. The main oncogenic factors in the field of thoracic oncology are mutations of EGFR, KRAS, and EML4-ALK translocation, which are most often reported in adenocarcinomas. However, new molecular targets have been highlighted recently including BRAF mutations, HER2 or PI3K, new translocations such as ROS1 or KIF5B-RET. Molecular...

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Source

Identifiers

PMID: 26076869
DOI: 10.1016/j.rmr.2015.02.091

Genes

ALK
BRAF
EGFR
EML4
KRAS
RET
ROS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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