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Article

Extracellular vesicle-mediated delivery of molecular compounds into gametes and embryos: learning from nature

12 Jun 2015

Abstract excerpt

BACKGROUND: Currently, even the most sophisticated methods of assisted reproductive technology (ART) allow us to achieve live births in only approximately 30% of patients, indicating that our understanding of the fine mechanisms underlying reproduction is far from ideal. One of the main challenges associated with studies of gamete structure and function is that these cells are remarkably resistant towards the...

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PMID: 26071427
DOI: 10.1093/humupd/dmv027

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