Article
The UDP-glucose: glycoprotein glucosyltransferase (UGGT), a key enzyme in ER quality control, plays a significant role in plant growth as well as biotic and abiotic stress in Arabidopsis thaliana.
BMC plant biology - 28 May 2015
Blanco-Herrera Francisca, Moreno Adrián A, Tapia Rodrigo, Reyes Francisca, Araya Macarena, D'Alessio Cecilia, Parodi Armando, Orellana Ariel
Abstract excerpt
BACKGROUND: UDP-glucose: glycoprotein glucosyltransferase (UGGT) is a key player in the quality control mechanism (ER-QC) that newly synthesized glycoproteins undergo in the ER. It has been shown that the UGGT Arabidopsis orthologue is involved in ER-QC; however, its role in plant physiology remains unclear. RESULTS: Here, we show that two mutant alleles in the At1g71220 locus have none or reduced UGGT activity....
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